{"id":25440,"date":"2016-03-08T11:53:58","date_gmt":"2016-03-08T10:53:58","guid":{"rendered":"https:\/\/www.ita.es\/proyecto\/prenomon\/"},"modified":"2023-11-30T09:07:58","modified_gmt":"2023-11-30T08:07:58","slug":"prenomon","status":"publish","type":"proyecto","link":"https:\/\/www.ita.es\/en\/project\/prenomon\/","title":{"rendered":"PRENOMON"},"content":{"rendered":"\r\n
\r\n
\r\n \n

General project data<\/h2>\n\n\n\n
  • Description<\/strong>: Development of a system of \npreservation of organs for transplantation capable of maintaining the organ in \nfunctional conditions during the preservation process. From this \nnot only the objective of preserving the organ in its original form, but also the \nconditions, but also to monitor the metabolic parameters of the\n during the preservation process, to regulate the values of the \nand determine its post-transplant viability. CHALLENGES-COLLABORATION \n2016.<\/li>
  • File number:<\/strong> RTC-2016-5108-1.<\/li>
  • Date of grant<\/strong>: 08\/03\/2016.<\/li>
  • Execution dates<\/strong>: 31\/12\/2019.<\/li><\/ul>\n\n\n\n

    Presentation and objectives<\/h2>\n\n\n\n

    \nTransplantation is the best technique available for the treatment of \nterminal failure of most of the essential organs, with the majority of the \nbenefited more than 1 million patients worldwide in the past. \ntransplantation of an organ.\n\nSpain has been the world leader for the past 22 years in terms of the number of \ntransplants per capita that are performed annually. However, despite \nto the clinical success of organ transplantation, the current demand for organ\n far exceeds the supply of donors. According to the World Registry of \nTransplants, the approximately 115,000 transplants performed in 2013. \nonly covered 10% of the world’s needs.\n\nMortality rates while awaiting transplantation are found to be \nin the range of 15-30%, and in some reports in the range of 15-30% in \nfunction of the organ in question.\n\nIn this regard, the development of new preservation systems, \nevaluation and treatment of organs for transplantation takes on an important role in the \npreservation methods based on the use of the traditional method of preservation.\n cold storage lacks the necessary capacity to valorize\n these organs. Therefore, the introduction of new systems of \npreservation will be essential for the development of the \norgan transplantation in the coming years.\n\nThe main objective of this project is the development of a system of\n preservation of organs for transplantation capable of maintaining the organ in \nfunctional conditions during the preservation process. To this end, \nThe system shall be capable of maintaining the conditions of \nand to supply the organ with oxygen and nutrients. \nnutrients necessary for its functioning.\n\nThe PRENOMON project will be valid for the preservation of kidney and liver and\n focuses on two basic developments:\n<\/p>\n\n\n\n

    1. On the one hand, the device capable of providing the conditions for\n preservation, which does not come into contact with the organ.<\/li>
    2. On the other hand, the components that come into contact with the organ or perfusion medium.<\/li><\/ol>\n\n\n\n

      \nIn order to achieve the main objective, it will be necessary to achieve the following secondary objectives:\n<\/p>\n\n\n\n

      1. Development of a system capable of providing the conditions for \ntemperature, flow rate, pressure, etc., that simulate the physiological state that\n the organ experiences in-vivo.<\/li>
      2. Development of a software capable of controlling with precision \nparameters, as well as the proper management of the \ninteraction with the user.<\/li>
      3. Development of on-line sensors capable of providing real-time measurements of the metabolic parameters of the organ.<\/li>
      4. Development of a disposable perfusion circuit, containing \nthe elements necessary to direct the perfusion medium into the \norgan, as well as the chamber to keep the organ in good condition. \nand temperature.<\/li><\/ol>\n\n\n\n

        Participating entities<\/h2>\n\n\n\n

        \nThe MODCOMP project has 17 partners<\/strong> from different countries. \nEuropean countries: Spain, the United Kingdom, Portugal, Italy, Greece, Belgium and\n Sweden. Among them, those who collaborate with ITAINNOVA in the field of\n computer simulation<\/strong> are:\n<\/p>\n\n\n\n

        • EBERS Medical Technology, S.L. (Project leader).<\/li>
        • BEONCHIP, S.L.<\/li>
        • AITIIP FOUNDATION.<\/li>
        • University of Zaragoza.<\/li>
        • Instituto Tecnol\u00f3gico de Arag\u00f3n, ITAINNOVA (Spain).<\/li><\/ul>\n\n\n\n

          Call for applications<\/h2>\n\n\n\n

          \nState Program for Research, Development and Innovation Oriented towards \nthe Challenges of Society, within the framework of the State Plan of Research \nScientific and Technical and Innovation 2013-2016.\n<\/p>\n\n\n\n

          Budget<\/h2>\n\n\n\n
          • Total bankable budget of the project: 691,482.27 .<\/li>
          • ITAINNOVA’s bankable budget: 68,120.50 .<\/li><\/ul>\n\n\n\n

            Financing<\/h2>\n\n\n\n
            • Total project grant: 131,472.76 .<\/li>
            • Total project loan: 431,793.23 .<\/li>
            • Grant to ITAINNOVA: 68,120.50 .<\/li><\/ul>\n\n\n\n

              \n This project has been co-funded by the Ministry of Economy, Industry and Competitiveness, within the State Program for Research, Development and Innovation Oriented to the Challenges of Society, in the framework of the State Plan for Scientific and Technical Research and Innovation 2013-2016.<\/em>\n <\/p>\n\n\n\n

              <\/p>\n\n\n\n

              <\/p>\n\n\n\n

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